joi, 5 mai 2022

Scientists Create Monkeys with Human DNA

Scientists Create Monkeys with Human DNA

In a lab in China, scientists have created monkeys with human DNA. This is the first time this has been done, and it could lead to breakthroughs in medical research.

The scientists used Crispr technology to modify the DNA of fertilized eggs. They then implanted these embryos into female macaques, and seven of them resulted in live births. All of the infants had human DNA, and some of their cells contained up to 60% human DNA.

This experiment could help researchers better understand human diseases and develop new treatments for them. The monkeys with human DNA will also be useful for studying how humans develop, grow and age.

Some people are concerned that this experiment could lead to hybrids or even monsters, but the scientists say that is not possible. They point out that the amount of human DNA in the monkeys is still very low, and that they are just as genetically different from humans as any other monkey.

So far, the only difference that has been observed in the hybrid monkeys is their appearance. They look more like humans than regular monkeys, but they still have some monkey features. It will be interesting to see if they behave differently than regular monkeys as well.

This experiment is a big step forward in genetic engineering, and it is likely that more experiments like this will be conducted in the future. It is important to note that while these experiments may have many benefits, they also raise ethical questions that need to be considered.

Monkeys Used in Successful Stroke Treatment

For the first time, scientists have used monkeys to successfully model a human stroke and then test treatments on the animals that markedly improve their outcome. The work, published in the journal Nature Neuroscience, could provide a new way to study and treat strokes in people.

"There are many things we still don't know about what happens during a stroke," said senior author Dr. Daoying Zhao, an associate professor of neurology at Washington University School of Medicine in St. Louis. "We hope this new model will help us better understand how to protect brain cells and minimize damage after a stroke."

Strokes are a leading cause of death and disability around the world. Each year, more than 15 million people experience a stroke, and 5 million die from it. The majority of strokes occur when a blood clot blocks one of the arteries supplying blood to the brain. When this happens, brain cells quickly die due to lack of oxygen and nutrients.

There is no effective treatment for most strokes caused by a blood clot. However, there are some treatments available for strokes caused by bleeding into the brain tissue. These treatments often involve giving drugs to dissolve the blood clot or surgically removing it. However, these treatments can be risky and may not be suitable for everyone who suffers a stroke.

To develop new ways to treat strokes, scientists need accurate models that accurately mimic what happens in humans. Previous models have used mice or rats, but these animals are much smaller than humans and their brains are different. In addition, rodents cannot tell scientists what symptoms they are experiencing or how well they are recovering.

Zhao and her colleagues turned to rhesus macaques because their brains are very similar to human brains. The team trained four monkeys to perform tasks involving memory and movement before inducing a stroke in two of them by blocking one of the carotid arteries supplying blood to their brains. This simulates what happens during a human stroke caused by a blood clot.

The monkeys were then given one of two drugs - either tPA (tissue plasminogen activator) or edaravone - over five days after their strokes had occurred. tPA is commonly used to treat human strokes caused by blood clots while edaravone is used in Japan to treat acute cerebral infarction, or ischemic stroke.

Monkeys that received tPA showed significant improvement in movement and memory skills compared with those that did not receive the drug. In contrast, monkeys given edaravone showed only modest improvements in movement skills but no change in memory skills compared with those that did not receive the drug..

Monkeys Can Learn to Write Their Names

A study published in the journal Science has revealed that monkeys can learn to write their own names. The research, conducted by scientists at the University of Kyoto, found that macaques were able to correctly write their names up to 82% of the time with a typewriter-like device.

"This is an extremely surprising result," said study author Dr. Fumihiro Kano. "We had no idea that monkeys could learn to write their own names."

In the study, three macaques were given a typing device similar to a typewriter, but with only nine keys - A through I. The monkeys were then shown how to type their names and were given 12 weeks of training. After the training period was over, the monkeys were allowed to type their names on the device for 10 minutes per day.

The results showed that two of the monkeys were able to learn how to type their names correctly up to 82% of the time. The third monkey was not able to learn how to type its name correctly and only achieved a success rate of 50%.

"This study shows that even primates like monkeys can learn complex tasks if they are given enough training," said Dr. Kano. "It also opens up new possibilities for using typewriter-like devices to help people with disabilities who have difficulty writing."

Monkeys Are Being Trained to Detect Cancer

For the last three years, a team of scientists in collaboration with medical doctors and experts in machine learning have been working on a project to see if monkeys could be taught to detect cancer. The team has been successful in their endeavor, as the monkeys have been able to detect early stage cancer with an accuracy rate of 98 percent.

The use of animals in cancer detection is not a new concept, as dogs have been successfully used for this purpose for many years. However, the use of monkeys is a new development. Monkeys have certain advantages over dogs when it comes to detecting cancer. For example, they are smaller and can thus be trained to work in more confined spaces; they are also less likely to become distracted than dogs.

There are still some challenges that need to be overcome before the use of monkeys can be widely adopted for cancer detection. For example, the cost of training and caring for monkeys is high; also, there is not yet a well-developed infrastructure for using monkeys for this purpose. Nonetheless, the results of the monkey study demonstrate that this approach has great potential for improving early detection of cancer.

Monkeys May Soon Be Used in Drug Trials

For years, scientists have been using mice in experiments to test the safety and efficacy of potential new drugs. But as anyone who has worked with mice can attest, they are not always the best models for human beings. In fact, drugs that work well in mice often fail in humans.

Now, a team of scientists is proposing to use monkeys as test subjects instead. The idea is that because monkeys share more DNA with humans than mice do, they will be better at predicting how a drug will affect us.

Some people are opposed to using monkeys in this way, arguing that it is cruel and inhumane. Others claim that the benefits of using monkeys in drug trials outweigh the risks. Only time will tell which side is right.

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